After beginning her career on stage, Anderson achieved international recognition for her role as FBI Special Agent Dana Scully on the American sci-fi drama series The X-Files.
Her film work includes the dramas The Mighty Celt (2005), The Last King of Scotland (2006), Shadow Dancer (2012), Viceroy's House (2017) and two X-Files films: The X-Files: Fight the Future (1998) and The X-Files: I Want to Believe (2008).
Aside from film and television, Anderson has taken on the stage and received both awards and critical acclaim.
Her stage work includes Absent Friends (1991) – for which she won a Theatre World Award for Best Newcomer, A Doll's House (2009) – that earned her a Laurence Olivier Award nomination, and a portrayal of Blanche Du Bois in A Streetcar Named Desire (2014, 2016) – for which she won the Evening Standard Theatre Award for Best Actress and received her second Laurence Olivier Award nomination for Best Actress.
Anderson recalled: "First of all, I swore I'd never move to Los Angeles, and once I did, I swore I'd never do television.
It was only after being out of work for almost a year that I began going in [to auditions] on some stuff that I would pray that I wouldn't get because I didn't want to be involved in it." As a result of this guest appearance, Anderson was sent the script for The X-Files.
Anderson is the co-writer of The Earth End Saga novel trilogy and the self-help guide book WE: A Manifesto for Women Everywhere.
Bedelia Du Maurier on Hannibal (2013–2015), and Media on American Gods (2017).He was in his second year of a Ph D program in Developmental Psychology at Stanford University when he was diagnosed with glioblastoma in 2008.With her English accent and background, she was mocked and felt out of place as a teenager in the American Midwest and soon adopted a Midwestern accent.She was voted by her classmates as "class clown", "most bizarre girl" and "most likely to be arrested".She was, in fact, arrested on graduation night for breaking and entering into her high school in an attempt to glue the locks of the doors.